We want all our patients to feel comfortable and confident during their procedures. The Pro-Nox™ Aesthetic System uses a 50/50 combination of inhaled oxygen and nitrous oxide to provide fast-acting pain relief. Nitrous, commonly known as laughing gas, is one of the oldest sedatives in medicine. While it is not a replacement for anesthesia, it does complement and enhance the effects of local anesthetics, like lidocaine.